LZTS1 Antibody
| Code | Size | Price |
|---|
| PSI-56-831-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Leucine zipper putative tumor suppressor 1, F37/esophageal cancer-related gene-coding leucine-zipper motif, Fez1, LZTS1, FEZ1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a tumor suppressor protein that is
ubiquitously expressed in normal tissues. In uveal melanomas,
expression of this protein is silenced in rapidly metastasizing and
metastatic tumor cells but has normal expression in slowly
metastasizing or nonmetastasizing tumor cells. This protein may
have a role in cell-cycle control by interacting with the
Cdk1/cyclinB1 complex. This gene is located on chromosomal region
8p22. Loss of heterozygosity (LOH) in the 8p arm is a common
characteristic of many types of cancer.
Background References:
- Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
- Chattopadhyay, I., et al. Mutat. Res. 696(2):130-138(2010)
- Califano, D., et al. J. Cell. Physiol. 222(2):382-386(2010)
- Shyn, S.I., et al. Mol. Psychiatry (2009) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LZTS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 77-105 amino acids from the N-terminal region of human LZTS1.
NCBI Gene ID #:
11178
NCBI Official Name:
Leucine zipper putative tumor suppressor 1
NCBI Official Symbol:
LZTS1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
67 kDa
Protein Accession #:
Q9Y250
Protein GI Number:
46396556
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle
Swissprot #:
Q9Y250
User NOte:
Optimal dilutions for each application to be determined by the researcher.