TIMP4 Antibody

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ProSci
Product Code: PSI-55-060
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-55-060-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Hela cell line lysates (35ug/lane).
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Western blot analysis in mouse brain tissue lysates (35ug/lane).
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Western blot analysis in Hela cell line lysates (35ug/lane).
Western blot analysis in mouse brain tissue lysates (35ug/lane).

Documents

Further Information

Additional Names:
Metalloproteinase inhibitor 4, Tissue inhibitor of metalloproteinases 4, TIMP-4, TIMP4
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.
Background References:
  • Nalpas, B., et al. Gut 59(8):1120-1126(2010)
  • Bailey, S.D., et al. Diabetes Care (2010) In press :
  • Wojciechowski, R., et al. Invest. Ophthalmol. Vis. Sci. (2010) In press :
  • Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TIMP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-74 amino acids from the Central region of human TIMP4.
NCBI Gene ID #:
7079
NCBI Official Name:
Metalloproteinase inhibitor 4
NCBI Official Symbol:
TIMP4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
Protein Accession #:
Q99727
Protein GI Number:
3915135
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle
Swissprot #:
Q99727
User NOte:
Optimal dilutions for each application to be determined by the researcher.