ANGPT1 Antibody
| Code | Size | Price |
|---|
| PSI-55-185-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Angiopoietin-1, ANG-1, ANGPT1, KIAA0003
Application Note:
For WB starting dilution is: 1:2000
Background:
Angiopoietins are proteins with important roles in
vascular development and angiogenesis. All angiopoietins bind with
similar affinity to an endothelial cell-specific tyrosine-protein
kinase receptor. The protein encoded by this gene is a secreted
glycoprotein that activates the receptor by inducing its tyrosine
phosphorylation. It plays a critical role in mediating reciprocal
interactions between the endothelium and surrounding matrix and
mesenchyme. The protein also contributes to blood vessel maturation
and stability, and may be involved in early development of the
heart.
Background References:
- Fang, X., et al. J. Biol. Chem. 285(34):26211-26222(2010)
- Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
- Choe, J.Y., et al. Joint Bone Spine 77(4):340-344(2010)
- Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Pig, Bovine
Immunogen:
This ANGPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-402 amino acids from the C-terminal region of human ANGPT1.
NCBI Gene ID #:
284
NCBI Official Name:
Angiopoietin-1
NCBI Official Symbol:
ANGPT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
Q15389
Protein GI Number:
12229574
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Cell Cycle,Obesity
Swissprot #:
Q15389
User NOte:
Optimal dilutions for each application to be determined by the researcher.