MMP11 Antibody
| Code | Size | Price |
|---|
| PSI-62-168-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Stromelysin-3, SL-3, ST3, 3424-, Matrix metalloproteinase-11, MMP-11, MMP11, STMY3
Application Note:
For WB starting dilution is: 1:1000
Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP11 may play an important role in the progression of epithelial malignancies. It is specifically expressed in stromal cells of breast carcinomas.
Background References:
- Anglard, P., et al., J. Biol. Chem. 270(35):20337-20344 (1995).
- Basset, P., et al., Nature 348(6303):699-704 (1990).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MMP11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 398-426 amino acids from the C-terminal region of human MMP11.
NCBI Gene ID #:
4320
NCBI Official Name:
Stromelysin-3
NCBI Official Symbol:
MMP11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
P24347
Protein GI Number:
317373418
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
P24347
User NOte:
Optimal dilutions for each application to be determined by the researcher.