Kallikrein 5 Antibody
| Code | Size | Price |
|---|
| PSI-62-246-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Kallikrein-5, 3421-, Kallikrein-like protein 2, KLK-L2, Stratum corneum tryptic enzyme, KLK5, SCTE
Application Note:
For WB starting dilution is: 1:1000
Background:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK5 expression is up-regulated by estrogens and progestins. The protein is secreted and may be involved in desquamation in the epidermis.
Background References:
- Planque, C., et al., Biochem. Biophys. Res. Commun. 329(4):1260-1266 (2005). Michael, I.P., et al., J. Biol. Chem. 280(15):14628-14635 (2005). Ishida-Yamamoto, A., et al., J. Invest. Dermatol. 124(2):360-366 (2005). Brattsand, M., et al., J. Invest. Dermatol. 124(1):198-203 (2005). Caubet, C., et al., J. Invest. Dermatol. 122(5):1235-1244 (2004).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Kallikrein 5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-174 amino acids from the Central region of human Kallikrein 5.
NCBI Gene ID #:
25818
NCBI Official Name:
Kallikrein-5
NCBI Official Symbol:
KLK5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
32 kDa
Protein Accession #:
Q9Y337
Protein GI Number:
296434569
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Cell Cycle,Signal Transduction
Swissprot #:
Q9Y337
User NOte:
Optimal dilutions for each application to be determined by the researcher.