MLXIPL Antibody
| Code | Size | Price |
|---|
| PSI-56-508-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Carbohydrate-responsive element-binding protein, ChREBP, Class D basic helix-loop-helix protein 14, bHLHd14, MLX interactor, MLX-interacting protein-like, WS basic-helix-loop-helix leucine zipper protein, WS-bHLH, Williams-Beuren syndrome chromosomal region 14 protein, MLXIPL, BHLHD14, MIO, WBSCR14
Application Note:
For WB starting dilution is: 1:2000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a basic helix-loop-helix leucine zipper
transcription factor of the Myc/Max/Mad superfamily. This protein
forms a heterodimeric complex and binds and activates, in a
glucose-dependent manner, carbohydrate response element (ChoRE)
motifs in the promoters of triglyceride synthesis genes. The gene
is deleted in Williams-Beuren syndrome, a multisystem developmental
disorder caused by the deletion of contiguous genes at chromosome
7q11.23.
Background References:
- Hu, M., et al. Pharmacogenet. Genomics 20(10):634-637(2010)
- Johansen, C.T., et al. Nat. Genet. 42(8):684-687(2010)
- Keebler, M.E., et al. Circ Cardiovasc Genet 3(4):358-364(2010)
- Chidambaram, M., et al. Metab. Clin. Exp. (2010) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MLXIPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 624-653 amino acids from the C-terminal region of human MLXIPL.
NCBI Gene ID #:
51085
NCBI Official Name:
Carbohydrate-responsive element-binding protein
NCBI Official Symbol:
MLXIPL
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
93 kDa
Protein Accession #:
Q9NP71
Protein GI Number:
20140871
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity
Swissprot #:
Q9NP71
User NOte:
Optimal dilutions for each application to be determined by the researcher.