SGMS2 Antibody
| Code | Size | Price |
|---|
| PSI-64-088-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Phosphatidylcholine:ceramide cholinephosphotransferase 2, Sphingomyelin synthase 2, SGMS2, SMS2
Application Note:
For WB starting dilution is: 1:1000
Background:
Sphingomyelin, a major component of cell and Golgi membranes, is made by the transfer of phosphocholine from phosphatidylcholine onto ceramide, with diacylglycerol as a side product. SGMS2 is an enzyme that catalyzes this reaction primarily at the cell membrane. The synthesis is reversible, and this enzyme can catalyze the reaction in either direction. This protein is required for cell growth.
Background References:
- Ternes, P., et al. J. Lipid Res. 50(11):2270-2277(2009)
- Liu, J., et al. Arterioscler. Thromb. Vasc. Biol. 29(6):850-856(2009)
- Tani, M., et al. Biochem. Biophys. Res. Commun. 381(3):328-332(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Rat
Immunogen:
This SGMS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 338-365 amino acids from the C-terminal region of human SGMS2.
NCBI Gene ID #:
166929
NCBI Official Name:
Phosphatidylcholine:ceramide cholinephosphotransferase 2
NCBI Official Symbol:
SGMS2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
Q8NHU3
Protein GI Number:
44888519
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
Q8NHU3
User NOte:
Optimal dilutions for each application to be determined by the researcher.