CPT2 Antibody

ProSci
Product Code: PSI-61-416
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-61-416-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of anti-CPT2 Pab in mouse kidney tissue lysate (35ug/lane)
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Confocal immunofluorescent analysis of CPT2 Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).

Western blot analysis of anti-CPT2 Pab in mouse kidney tissue lysate (35ug/lane)
Confocal immunofluorescent analysis of CPT2 Antibody with HepG2 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).

Further Information

Additional Names:
Carnitine O-palmitoyltransferase 2, mitochondrial, Carnitine palmitoyltransferase II, CPT II, CPT2, CPT1
Application Note:
For WB starting dilution is: 1:1000

For IF starting dilution is: 1:10~50
Background:
Carnitine palmitoyltransferase II precursor (CPT2) is a nuclear protein which is transported to the mitochondrial inner membrane. CPT2 together with carnitine palmitoyltransferase I oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders.
Background References:
  • Deschauer, M., et al., Mol. Genet. Metab. 75(2):181-185 (2002).
  • Haap, M., et al., J. Clin. Endocrinol. Metab. 87(5):2139-2143 (2002).
  • Britton, C.H., et al., Proc. Natl. Acad. Sci. U.S.A. 92(6):1984-1988 (1995).
  • Verderio, E., et al., Hum. Mol. Genet. 4(1):19-29 (1995).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CPT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 431-462 amino acids from the C-terminal region of human CPT2.
NCBI Gene ID #:
1376
NCBI Official Name:
Carnitine O-palmitoyltransferase 2, mitochondrial
NCBI Official Symbol:
CPT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
74 kDa
Protein Accession #:
P23786
Protein GI Number:
416836
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P23786
User NOte:
Optimal dilutions for each application to be determined by the researcher.