Mouse Prkaca/Prkacb Antibody

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ProSci
Product Code: PSI-57-746
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-746-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the Prkaca/Prkacb antibody detected the Prkaca/Prkacb protein (arrow).
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Western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Prkaca/Prkacb antibody detected the Prkaca/Prkacb protein (arrow).
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Western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the Prkaca/Prkacb antibody detected the Prkaca/Prkacb protein (arrow).
Western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Prkaca/Prkacb antibody detected the Prkaca/Prkacb protein (arrow).

Documents

Further Information

Additional Names:
cAMP-dependent protein kinase catalytic subunit beta, PKA C-beta, Prkacb, Pkacb
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux.
Background References:
  • Ribeiro, R.A., et al. Br. J. Nutr. 104(8):1148-1155(2010)
  • Liu, J.X., et al. Seizure 19(7):414-420(2010)
  • Ha, C.H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(35):15467-15472(2010)
  • Sarma, S., et al. Proc. Natl. Acad. Sci. U.S.A. 107(29):13165-13170(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Pig, Rat
Immunogen:
This Mouse Prkaca/Prkacb antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 292-319 amino acids from the C-terminal region of mouse Prkaca/Prkacb.
NCBI Gene ID #:
18749
NCBI Official Name:
cAMP-dependent protein kinase catalytic subunit beta
NCBI Official Symbol:
Prkacb
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
P68181
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Obesity,Signal Transduction
Swissprot #:
P68181
User NOte:
Optimal dilutions for each application to be determined by the researcher.