LPXN Antibody
| Code | Size | Price |
|---|
| PSI-59-444-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Leupaxin, LPXN, LDLP
Application Note:
For WB starting dilution is: 1:1000
Background:
The product encoded by this gene is preferentially
expressed in hematopoietic cells and belongs to the paxillin
protein family. Similar to other members of this
focal-adhesion-associated adaptor-protein family, it has four
leucine-rich LD-motifs in the N-terminus and four LIM domains in
the C-terminus. It may function in cell type-specific signaling by
associating with PYK2, a member of focal adhesion kinase family. As
a substrate for a tyrosine kinase in lymphoid cells, this protein
may also function in, and be regulated by, tyrosine kinase
activity. Alternative splicing results in multiple transcript
variants encoding distinct isoforms.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Tanaka, T., et al. Cancer Sci. 101(2):363-368(2010)
- Dai, H.P., et al. Genes Chromosomes Cancer 48(12):1027-1036(2009)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LPXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-257 amino acids from the Central region of human LPXN.
NCBI Gene ID #:
9404
NCBI Official Name:
Leupaxin
NCBI Official Symbol:
LPXN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
O60711
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
O60711
User NOte:
Optimal dilutions for each application to be determined by the researcher.