NET1 Antibody

ProSci
Product Code: PSI-59-160
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-160-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Hela cell line lysates (35ug/lane).
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Western blot analysis in mouse lung tissue lysates (35ug/lane).

Western blot analysis in Hela cell line lysates (35ug/lane).
Western blot analysis in mouse lung tissue lysates (35ug/lane).

Further Information

Additional Names:
Neuroepithelial cell-transforming gene 1 protein, Proto-oncogene p65 Net1, Rho guanine nucleotide exchange factor 8, NET1, ARHGEF8
Application Note:
For WB starting dilution is: 1:1000
Background:
NET1 acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway (By similarity).
Background References:
  • Lee, J., et al. J. Biol. Chem. 285(34):26618-26627(2010)
  • Carr, H.S., et al. J. Biol. Chem. 284(36):24269-24280(2009)
  • Gilcrease, M.Z., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):80-86(2009)
  • Murray, D., et al. Br. J. Cancer 99(8):1322-1329(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NET1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 356-385 amino acids from the Central region of human NET1.
NCBI Gene ID #:
10276
NCBI Official Name:
Neuroepithelial cell-transforming gene 1 protein
NCBI Official Symbol:
NET1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
Q7Z628
Protein GI Number:
52782735
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q7Z628
User NOte:
Optimal dilutions for each application to be determined by the researcher.