Mouse Jak3 Antibody

ProSci
Product Code: PSI-57-601
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-601-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 2
Western blot analysis in K562 cell line lysates (35ug/lane).
2 / 2
Western blot analysis in mouse stomach tissue lysates (35ug/lane).

Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in mouse stomach tissue lysates (35ug/lane).

Further Information

Additional Names:
Tyrosine-protein kinase JAK3, Janus kinase 3, JAK-3, Jak3
Application Note:
For WB starting dilution is: 1:1000
Background:
Tyrosine kinase of the non-receptor type, involved in the interleukin-2 and interleukin-4 signaling pathway. Phosphorylates STAT6, IRS1, IRS2 and PI3K.
Background References:
  • Martin, P., et al. Mol. Cell. Biol. 30(20):4877-4889(2010)
  • Lange, C., et al. J. Neurochem. 113(5):1210-1220(2010)
  • Shi, M., et al. J. Immunol. 183(7):4493-4501(2009)
  • Chang, B.Y., et al. J. Immunol. 183(3):2183-2192(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This Mouse Jak3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-161 amino acids from the N-terminal region of mouse Jak3.
NCBI Gene ID #:
16453
NCBI Official Name:
Tyrosine-protein kinase JAK3
NCBI Official Symbol:
Jak3
NCBI Organism:
Mus musculus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
123 kDa
Protein Accession #:
Q62137
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q62137
User NOte:
Optimal dilutions for each application to be determined by the researcher.