CDH11 Antibody
| Code | Size | Price |
|---|
| PSI-59-952-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cadherin-11, OSF-4, Osteoblast cadherin, OB-cadherin, CDH11
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a type II classical cadherin from the
cadherin superfamily, integral membrane proteins that mediate
calcium-dependent cell-cell adhesion. Mature cadherin proteins are
composed of a large N-terminal extracellular domain, a single
membrane-spanning domain, and a small, highly conserved C-terminal
cytoplasmic domain. Type II (atypical) cadherins are defined based
on their lack of a HAV cell adhesion recognition sequence specific
to type I cadherins. Expression of this particular cadherin in
osteoblastic cell lines, and its upregulation during
differentiation, suggests a specific function in bone development
and maintenance.
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Sachdeva, M., et al. Cancer Res. 70(1):378-387(2010)
- Canova, C., et al. Cancer Res. 69(7):2956-2965(2009)
- Farina, A.K., et al. PLoS ONE(3), E4797 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CDH11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 622-650 amino acids from the C-terminal region of human CDH11.
NCBI Gene ID #:
1009
NCBI Official Name:
Cadherin-11
NCBI Official Symbol:
CDH11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
88 kDa
Protein Accession #:
P55287
Protein GI Number:
146345381
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
P55287
User NOte:
Optimal dilutions for each application to be determined by the researcher.