LOXL4 Antibody
Code | Size | Price |
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PSI-59-061-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Lysyl oxidase homolog 4, 143-, Lysyl oxidase-like protein 4, Lysyl oxidase-related protein C, LOXL4, LOXC
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the lysyl oxidase gene
family. The prototypic member of the family is essential to the
biogenesis of connective tissue, encoding an extracellular
copper-dependent amine oxidase that catalyses the first step in the
formation of crosslinks in collagens and elastin. A highly
conserved amino acid sequence at the C-terminus end appears to be
sufficient for amine oxidase activity, suggesting that each family
member may retain this function. The N-terminus is poorly conserved
and may impart additional roles in developmental regulation,
senescence, tumor suppression, cell growth control, and chemotaxis
to each member of the family.
Background References:
- Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
- Sebban, S., et al. Virchows Arch. 454(1):71-79(2009)
- Gorogh, T., et al. Int. J. Oncol. 33(5):1091-1098(2008)
- Kim, D.J., et al. Biochem. Biophys. Res. Commun. 373(4):521-527(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LOXL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-603 amino acids from the C-terminal region of human LOXL4.
NCBI Gene ID #:
84171
NCBI Official Name:
Lysyl oxidase homolog 4
NCBI Official Symbol:
LOXL4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
84 kDa
Protein Accession #:
Q96JB6
Protein GI Number:
20177960
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q96JB6
User NOte:
Optimal dilutions for each application to be determined by the researcher.