CLDN22 Antibody

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ProSci
Product Code: PSI-55-099
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-55-099-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Jurkat cell line lysates (35ug/lane).
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Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).
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Western blot analysis in Jurkat cell line lysates (35ug/lane).
Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).

Documents

Further Information

Additional Names:
Claudin-22, CLDN22
Application Note:
For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50
Background:
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3' UTR of the WWC2 gene (GeneID: 80014) on the opposite strand.
Background References:
  • Lal-Nag, M., et al. Genome Biol. 10 (8), 235 (2009) :
  • Krause, G., et al. Biochim. Biophys. Acta 1778(3):631-645(2008)
  • Hillier, L.W., et al. Nature 434(7034):724-731(2005)
  • Katoh, M., et al. Int. J. Mol. Med. 11(6):683-689(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CLDN22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-117 amino acids from the Central region of human CLDN22.
NCBI Gene ID #:
53842
NCBI Official Name:
Claudin-22
NCBI Official Symbol:
CLDN22
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
25 kDa
Protein Accession #:
Q8N7P3
Protein GI Number:
62298548
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q8N7P3
User NOte:
Optimal dilutions for each application to be determined by the researcher.