FBLN1 Antibody

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ProSci
Product Code: PSI-57-902
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-902-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).
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Western blot analysis in human placenta tissue lysates (35ug/lane).
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Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).
Western blot analysis in human placenta tissue lysates (35ug/lane).

Documents

Further Information

Additional Names:
Fibulin-1, FIBL-1, FBLN1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Li, C., et al. Mol. Vis. 16, 689-697 (2010) :
  • Wooten, E.C., et al. PLoS ONE(1), E8830 (2010) :
  • Argraves, W.S., et al. Histochem. Cell Biol. 132(5):559-565(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FBLN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 622-650 amino acids from the C-terminal region of human FBLN1.
NCBI Gene ID #:
2192
NCBI Official Name:
Fibulin-1
NCBI Official Symbol:
FBLN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
77 kDa
Protein Accession #:
P23142
Protein GI Number:
215274249
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
P23142
User NOte:
Optimal dilutions for each application to be determined by the researcher.