PPM1L Antibody
| Code | Size | Price |
|---|
| PSI-55-550-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein phosphatase 1L, Protein phosphatase 1-like, Protein phosphatase 2C isoform epsilon, PP2C-epsilon, PPM1L, PP2CE
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
PPM1L, or PP2CE, belongs to the PP2C group of
serine/threonine phosphatases, which are distinguished from other
phosphatases by their structure, absolute requirement for Mg(2+) or
Mn(2+), and insensitivity to okadaic acid. PP2Cs regulate
stress-activated protein kinase (SAPK; see MIM 601158) signaling
cascades that respond to extracellular stimuli (Jin et al., 2004
[PubMed 15560375]).
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Thean, L.F., et al. Genes Chromosomes Cancer 49(2):99-106(2010)
- Trynka, G., et al. Gut 58(8):1078-1083(2009)
- Saito, S., et al. J. Biol. Chem. 283(10):6584-6593(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This PPM1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-244 amino acids from the C-terminal region of human PPM1L.
NCBI Gene ID #:
151742
NCBI Official Name:
Protein phosphatase 1L
NCBI Official Symbol:
PPM1L
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
Q5SGD2
Protein GI Number:
74743437
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cancer,Signal Transduction
Swissprot #:
Q5SGD2
User NOte:
Optimal dilutions for each application to be determined by the researcher.