CUL4A Antibody

ProSci
Product Code: PSI-57-322
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-322-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse testis tissue lysates (35ug/lane).
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Western blot analysis in Jurkat cell line lysates (35ug/lane).
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Western blot analysis in mouse testis tissue lysates (35ug/lane).
Western blot analysis in Jurkat cell line lysates (35ug/lane).

Further Information

Additional Names:
Cullin-4A, CUL-4A, CUL4A
Application Note:
For WB starting dilution is: 1:1000
Background:
CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al., 2009 [PubMed 19481525]).
Background References:
  • Aggarwal, P., et al. Cancer Cell 18(4):329-340(2010)
  • Abbas, T., et al. Mol. Cell 40(1):9-21(2010)
  • Lv, X.B., et al. J. Biol. Chem. 285(24):18234-18240(2010)
  • Kerzendorfer, C., et al. Hum. Mol. Genet. 19(7):1324-1334(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CUL4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human CUL4A.
NCBI Gene ID #:
8451
NCBI Official Name:
Cullin-4A
NCBI Official Symbol:
CUL4A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
88 kDa
Protein Accession #:
Q13619
Protein GI Number:
108936013
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q13619
User NOte:
Optimal dilutions for each application to be determined by the researcher.