HECW2 Antibody

ProSci
Product Code: PSI-58-661
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-661-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse brain tissue lysates (35ug/lane).

Western blot analysis in mouse brain tissue lysates (35ug/lane).

Further Information

Additional Names:
E3 ubiquitin-protein ligase HECW2, 632-, HECT, C2 and WW domain-containing protein 2, NEDD4-like E3 ubiquitin-protein ligase 2, HECW2, KIAA1301, NEDL2
Application Note:
For WB starting dilution is: 1:1000
Background:
E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.
Background References:
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Miyazaki, K., et al. Biochem. Biophys. Res. Commun. 308(1):106-113(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This HECW2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 848-876 amino acids from the Central region of human HECW2.
NCBI Gene ID #:
57520
NCBI Official Name:
E3 ubiquitin-protein ligase HECW2
NCBI Official Symbol:
HECW2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
176 kDa
Protein Accession #:
Q9P2P5
Protein GI Number:
126215718
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9P2P5
User NOte:
Optimal dilutions for each application to be determined by the researcher.