CDC25C Antibody

ProSci
Product Code: PSI-63-249
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-249-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of CDC25C Antibody in NIH-3T3 cell line lysates (35ug/lane)

Western blot analysis of CDC25C Antibody in NIH-3T3 cell line lysates (35ug/lane)

Further Information

Additional Names:
M-phase inducer phosphatase 3, Dual specificity phosphatase Cdc25C, CDC25C
Application Note:
For WB starting dilution is: 1:1000
Background:
CDC25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest.
Background References:
  • Varmeh,S., Mol. Cancer Ther.(12), 3789-3799 (2008)
  • Long,J.M., Cell Cycle(19), 3062-3073 (2008)
  • Bonnet,J., Cell Cycle(13), 1991-1998 (2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CDC25C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-142 amino acids from the Central region of human CDC25C.
NCBI Gene ID #:
995
NCBI Official Name:
M-phase inducer phosphatase 3
NCBI Official Symbol:
CDC25C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
P30307
Protein GI Number:
116242631
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle
Swissprot #:
P30307
User NOte:
Optimal dilutions for each application to be determined by the researcher.