ASB3 Antibody

ProSci
Product Code: PSI-58-696
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-696-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of ASB3 Antibody Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in A549 cell line lysate
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Western blot analysis of ASB3 Antibody Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in mouse spleen tissue lysate

Western blot analysis of ASB3 Antibody Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in A549 cell line lysate
Western blot analysis of ASB3 Antibody Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in mouse spleen tissue lysate

Further Information

Additional Names:
Ankyrin repeat and SOCS box protein 3, ASB-3, ASB3
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known.
Background References:
  • Yang, Q., et al. BMC Med. Genet.SUPPL 1, S12 (2007)Chung, A.S., et al. Mol. Cell. Biol. 25(11):4716-4726(2005) Kile, B.T., et al. Trends Biochem. Sci. 27(5):235-241(2002) Kile, B.T., et al. Mol. Cell. Biol. 21(18):6189-6197(2001) Kile, B.T., et al. Gene 258 (1-2), 31-41 (2000) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ASB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-42 amino acids from the N-terminal region of human ASB3.
NCBI Gene ID #:
100302652, 51130
NCBI Official Name:
Ankyrin repeat and SOCS box protein 3
NCBI Official Symbol:
ASB3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
Q9Y575
Protein GI Number:
20532004
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9Y575
User NOte:
Optimal dilutions for each application to be determined by the researcher.