DDX11 Antibody
| Code | Size | Price |
|---|
| PSI-55-186-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Flow Cytometry
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Probable ATP-dependent RNA helicase DDX11, CHL1-related protein 1, hCHLR1, DEAD/H box protein 11, Keratinocyte growth factor-regulated gene 2 protein, KRG-2, DDX11, CHL1, CHLR1, KRG2
Application Note:
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
DEAD box proteins, characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration
of RNA secondary structure such as translation initiation, nuclear
and mitochondrial splicing, and ribosome and spliceosome assembly.
Based on their distribution patterns, some members of this family
are believed to be involved in embryogenesis, spermatogenesis, and
cellular growth and division. DDX11 encodes a DEAD box protein,
which is an enzyme that possesses both ATPase and DNA helicase
activities. DDX11 is a homolog of the yeast CHL1 gene, and may
function to maintain chromosome transmission fidelity and genome
stability.
Background References:
- Leman, A.R., et al. J. Cell. Sci. 123 (PT 5), 660-670 (2010) :
- Farina, A., et al. J. Biol. Chem. 283(30):20925-20936(2008)
- Parish, J.L., et al. Mol. Cell 24(6):867-876(2006)
- Parish, J.L., et al. J. Cell. Sci. 119 (PT 23), 4857-4865 (2006) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DDX11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 656-683 amino acids from the Central region of human DDX11.
NCBI Gene ID #:
1663
NCBI Official Name:
Probable ATP-dependent RNA helicase DDX11
NCBI Official Symbol:
DDX11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
108 kDa
Protein Accession #:
Q96FC9
Protein GI Number:
74731686
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q96FC9
User NOte:
Optimal dilutions for each application to be determined by the researcher.