STAMBP Antibody
Code | Size | Price |
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PSI-56-589-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
STAM-binding protein, 3419-, Associated molecule with the SH3 domain of STAM, Endosome-associated ubiquitin isopeptidase, STAMBP, AMSH
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
Cytokine-mediated signal transduction in the JAK-STAT
cascade requires the involvement of adaptor molecules. One such
signal-transducing adaptor molecule contains an SH3 domain that is
required for induction of MYC and cell growth. The protein encoded
by this gene binds to the SH3 domain of the signal-transducing
adaptor molecule, and plays a critical role in cytokine-mediated
signaling for MYC induction and cell cycle progression. Multiple
alternatively spliced transcript variants encoding the same protein
isoform have been found for this gene.
Background References:
- Sierra, M.I., et al. J. Biol. Chem. 285(18):13990-14004(2010)
- Hasdemir, B., et al. J. Biol. Chem. 284(41):28453-28466(2009)
- Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
- Wang, P., et al. BMC Genomics 10, 518 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This STAMBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 355-383 amino acids from the C-terminal region of human STAMBP.
NCBI Gene ID #:
10617
NCBI Official Name:
STAM-binding protein
NCBI Official Symbol:
STAMBP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
48 kDa
Protein Accession #:
O95630
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
O95630
User NOte:
Optimal dilutions for each application to be determined by the researcher.