INSC Antibody
| Code | Size | Price |
|---|
| PSI-64-072-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein inscuteable homolog, INSC
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
In Drosophila, neuroblasts divide asymmetrically into
another neuroblast at the apical side and a smaller ganglion mother
cell on the basal side. Cell polarization is precisely regulated by
2 apically localized multiprotein signaling complexes that are
tethered by Inscuteable, which regulates their apical localization
(Izaki et al., 2006 [PubMed 16458856]).
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Vural, A., et al. Mol. Cell. Biol. 30(6):1528-1540(2010)
- Rivadeneira, F., et al. Nat. Genet. 41(11):1199-1206(2009)
- Izaki, T., et al. Biochem. Biophys. Res. Commun. 341(4):1001-1006(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This INSC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 409-437 amino acids from the C-terminal region of human INSC.
NCBI Gene ID #:
387755
NCBI Official Name:
Protein inscuteable homolog
NCBI Official Symbol:
INSC
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
63 kDa
Protein Accession #:
Q1MX18
Protein GI Number:
116248172
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Cell Cycle
Swissprot #:
Q1MX18
User NOte:
Optimal dilutions for each application to be determined by the researcher.