ZMPSTE24 Antibody

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ProSci
Product Code: PSI-61-385
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-61-385-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution Lane 1: A431 whole cell lysate Lane 2: human kidney lysate Lysates/proteins at 20 ug per lane.
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Antibody is used in Western blot to detect ZMPSTE24 in mouse cerebellum tissue lysate.
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Western Blot at 1:1000 dilution Lane 1: A431 whole cell lysate Lane 2: human kidney lysate Lysates/proteins at 20 ug per lane.
Antibody is used in Western blot to detect ZMPSTE24 in mouse cerebellum tissue lysate.

Documents

Further Information

Additional Names:
CAAX prenyl protease 1 homolog, Farnesylated proteins-converting enzyme 1, FACE-1, Prenyl protein-specific endoprotease 1, Zinc metalloproteinase Ste24 homolog, ZMPSTE24, FACE1, STE24
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.
Background References:
  • Freije, J.M., et al., Genomics 58(3):270-280 (1999).
  • Kumagai, H., et al., Biochim. Biophys. Acta 1426(3):468-474 (1999).
  • Tam, A., et al., J. Cell Biol. 142(3):635-649 (1998).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ZMPSTE24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-430 amino acids from the Central region of human ZMPSTE24.
NCBI Gene ID #:
10269
NCBI Official Name:
CAAX prenyl protease 1 homolog
NCBI Official Symbol:
ZMPSTE24
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
O75844
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle,Cell Cycle,Signal Transduction
Swissprot #:
O75844
User NOte:
Optimal dilutions for each application to be determined by the researcher.