PNPT1 Antibody

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ProSci
Product Code: PSI-59-288
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-288-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
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Western blot analysis in mouse kidney tissue lysates (35ug/lane).
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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Western blot analysis in mouse kidney tissue lysates (35ug/lane).

Documents

Further Information

Additional Names:
Polyribonucleotide nucleotidyltransferase 1, mitochondrial, 3'-5' RNA exonuclease OLD35, PNPase old-35, Polynucleotide phosphorylase 1, PNPase 1, Polynucleotide phosphorylase-like protein, PNPT1, PNPASE
Application Note:
For WB starting dilution is: 1:1000
Background:
PNPT1 is a subunit of the exosome complex, which is involved in 3-prime-to-5-prime exoribonuclease activity for RNA processing and degradation (Raijmakers et al., 2002 [PubMed 12419256]).
Background References:
  • Wang, G., et al. Cell 142(3):456-467(2010)
  • Das, S.K., et al. Proc. Natl. Acad. Sci. U.S.A. 107(26):11948-11953(2010)
  • Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
  • O'Doherty, C., et al. Pharmacogenomics 10(7):1177-1186(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PNPT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-311 amino acids from the Central region of human PNPT1.
NCBI Gene ID #:
87178
NCBI Official Name:
Polyribonucleotide nucleotidyltransferase 1, mitochondrial
NCBI Official Symbol:
PNPT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
86 kDa
Protein Accession #:
Q8TCS8
Protein GI Number:
115502437
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Immunology,Obesity
Swissprot #:
Q8TCS8
User NOte:
Optimal dilutions for each application to be determined by the researcher.