SEMA6D Antibody
| Code | Size | Price |
|---|
| PSI-58-787-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Semaphorin-6D, SEMA6D, KIAA1479
Application Note:
For WB starting dilution is: 1:1000
Background:
Semaphorins are a large family, including both secreted
and membrane associated proteins, many of which have been
implicated as inhibitors or chemorepellents in axon pathfinding,
fasciculation and branching, and target selection. All semaphorins
possess a semaphorin (Sema) domain and a PSI domain (found in
plexins, semaphorins and integrins) in the N-terminal extracellular
portion. Additional sequence motifs C-terminal to the semaphorin
domain allow classification into distinct subfamilies. Results
demonstrate that transmembrane semaphorins, like the secreted ones,
can act as repulsive axon guidance cues. This gene encodes a class
6 vertebrate transmembrane semaphorin that demonstrates alternative
splicing. Several transcript variants have been identified and
expression of the distinct encoded isoforms is thought to be
regulated in a tissue- and development-dependent manner. [provided
by RefSeq].
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
- Stokowski, R.P., et al. Am. J. Hum. Genet. 81(6):1119-1132(2007)
- Zhao, X.Y., et al. World J. Gastroenterol. 12(45):7388-7390(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SEMA6D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-48 amino acids from the N-terminal region of human SEMA6D.
NCBI Gene ID #:
80031
NCBI Official Name:
Semaphorin-6D
NCBI Official Symbol:
SEMA6D
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
120 kDa
Protein Accession #:
Q8NFY4
Protein GI Number:
74715611
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Neuroscience
Swissprot #:
Q8NFY4
User NOte:
Optimal dilutions for each application to be determined by the researcher.