RAGE Antibody
| Code | Size | Price |
|---|
| PSI-61-373-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Advanced glycosylation end product-specific receptor, Receptor for advanced glycosylation end products, AGER, RAGE
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
AGER is a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products.
Background References:
- Schlueter, C., et al., Biochim. Biophys. Acta 1630(1):1-6 (2003). Shanmugam, N., et al., J. Biol. Chem. 278(37):34834-34844 (2003). Kuniyasu, H., et al., Oncol. Rep. 10(2):445-448 (2003). Hsieh, H.L., et al., Biochem. Biophys. Res. Commun. 307(2):375-381 (2003). Rocken, C., et al., Am. J. Pathol. 162(4):1213-1220 (2003).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This RAGE (AGER) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-59 amino acids from the N-terminal region of human RAGE (AGER).
NCBI Gene ID #:
177
NCBI Official Name:
Advanced glycosylation end product-specific receptor
NCBI Official Symbol:
AGER
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
43 kDa
Protein Accession #:
Q15109
Protein GI Number:
2497317
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle,Neuroscience
Swissprot #:
Q15109
User NOte:
Optimal dilutions for each application to be determined by the researcher.