Sestrin-1 Antibody

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ProSci
Product Code: PSI-63-100
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-100-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Flow Cytometry
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of Sestrin-1 antibody in mouse heart tissue lysates (35ug/lane)
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Western blot analysis in NCI-H460,HL-60 cell line lysates (35ug/lane).This demonstrates the Sestrin-1 antibody detected the Sestrin-1 protein (arrow).
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Western blot analysis of Sestrin-1 antibody in mouse heart tissue lysates (35ug/lane)
Western blot analysis in NCI-H460,HL-60 cell line lysates (35ug/lane).This demonstrates the Sestrin-1 antibody detected the Sestrin-1 protein (arrow).

Documents

Further Information

Additional Names:
Sestrin-1, p53-regulated protein PA26, SESN1, PA26, SEST1
Application Note:
For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50
Background:
Sestrin-1 is involved in the reduction of peroxiredoxins. This protein may also be regulator of cellular growth.
Background References:
  • Budanov,A.V., Science 304 (5670), 596-600 (2004)
  • Peeters,H., Hum. Genet. 112 (5-6), 573-580 (2003)
  • Velasco-Miguel,S., Oncogene 18 (1), 127-137 (1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Xenopus
Immunogen:
This Sestrin-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-341 amino acids from the C-terminal region of human Sestrin-1.
NCBI Gene ID #:
27244
NCBI Official Name:
Sestrin-1
NCBI Official Symbol:
SESN1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
Q9Y6P5
Protein GI Number:
13633953
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle,Obesity
Swissprot #:
Q9Y6P5
User NOte:
Optimal dilutions for each application to be determined by the researcher.