L2HGDH Antibody
| Code | Size | Price |
|---|
| PSI-55-109-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
L-2-hydroxyglutarate dehydrogenase, mitochondrial, Duranin, L2HGDH, C14orf160
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes L-2-hydroxyglutarate dehydrogenase, a
FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to
alpha-ketoglutarate in a variety of mammalian tissues. Mutations in
this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal
recessive neurometabolic disorder resulting in moderate to severe
mental retardation.
Background References:
- Short, A.D., et al. Vet. Rec. 167(12):455-457(2010)
- Steenweg, M.E., et al. Hum. Mutat. 31(4):380-390(2010)
- Kranendijk, M., et al. Hum. Mutat. 31(3):279-283(2010)
- Vilarinho, L., et al. J. Hum. Genet. 55(1):55-58(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This L2HGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-159 amino acids from the Central region of human L2HGDH.
NCBI Gene ID #:
79944
NCBI Official Name:
L-2-hydroxyglutarate dehydrogenase, mitochondrial
NCBI Official Symbol:
L2HGDH
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
Q9H9P8
Protein GI Number:
317373422
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Signal Transduction
Swissprot #:
Q9H9P8
User NOte:
Optimal dilutions for each application to be determined by the researcher.