BCL7B Antibody

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ProSci
Product Code: PSI-58-996
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-996-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Y79 cell line lysates (35ug/lane).
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Western blot analysis in mouse heart tissue lysates (35ug/lane).
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Western blot analysis in Y79 cell line lysates (35ug/lane).
Western blot analysis in mouse heart tissue lysates (35ug/lane).

Documents

Further Information

Additional Names:
B-cell CLL/lymphoma 7 protein family member B, Hom s 3, BCL7B
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the BCL7 family including BCL7A, BCL7B and BCL7C proteins. This member is BCL7B, which contains a region that is highly similar to the N-terminal segment of BCL7A or BCL7C proteins. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. This gene is located at a chromosomal region commonly deleted in Williams syndrome. This gene is highly conserved from C. elegans to human. Multiple alternatively spliced transcript variants have been found for this gene.
Background References:
  • Fontaine-Bisson, B., et al. Diabetologia 53(10):2155-2162(2010)
  • Kathiresan, S., et al. Nat. Genet. 40(2):189-197(2008)
  • Willer, C.J., et al. Nat. Genet. 40(2):161-169(2008)
  • Olsen, J.V., et al. Cell 127(3):635-648(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This BCL7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-164 amino acids from the C-terminal region of human BCL7B.
NCBI Gene ID #:
9275
NCBI Official Name:
B-cell CLL/lymphoma 7 protein family member B
NCBI Official Symbol:
BCL7B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
Q9BQE9
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Obesity,Signal Transduction
Swissprot #:
Q9BQE9
User NOte:
Optimal dilutions for each application to be determined by the researcher.