ARL6IP5 Antibody

ProSci
Product Code: PSI-59-176
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-176-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).

Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).

Further Information

Additional Names:
PRA1 family protein 3, ADP-ribosylation factor-like protein 6-interacting protein 5, ARL-6-interacting protein 5, Aip-5, Cytoskeleton-related vitamin A-responsive protein, Dermal papilla-derived protein 11, GTRAP3-18, Glutamate transporter EAAC1-interacting protein, JM5, Prenylated Rab acceptor protein 2, Protein JWa, Putative MAPK-activating protein PM27, ARL6IP5, DERP11, JWA, PRA2, PRAF3
Application Note:
For WB starting dilution is: 1:1000
Background:
Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.
Background References:
  • Edenberg, H.J., et al. Alcohol. Clin. Exp. Res. 34(5):840-852(2010)
  • Akiduki, S., et al. J. Biol. Chem. 283(46):31323-31332(2008)
  • Ruggiero, A.M., et al. J. Biol. Chem. 283(10):6175-6183(2008)
  • Watabe, M., et al. Mol. Pharmacol. 72(5):1103-1110(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ARL6IP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-99 amino acids from the Central region of human ARL6IP5.
NCBI Gene ID #:
10550
NCBI Official Name:
PRA1 family protein 3
NCBI Official Symbol:
ARL6IP5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
22 kDa
Protein Accession #:
O75915
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
O75915
User NOte:
Optimal dilutions for each application to be determined by the researcher.