ADAMTS10 Antibody
| Code | Size | Price |
|---|
| PSI-55-037-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
A disintegrin and metalloproteinase with thrombospondin motifs 10, ADAM-TS 10, ADAM-TS10, ADAMTS-10, 3424-, ADAMTS10
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene belongs to the ADAMTS (a disintegrin and
metalloproteinase domain with thrombospondin type-1 motifs) family
of zinc-dependent proteases. ADAMTS proteases are complex secreted
enzymes containing a prometalloprotease domain of the reprolysin
type attached to an ancillary domain with a highly conserved
structure that includes at least one thrombospondin type 1 repeat.
They have been demonstrated to have important roles in connective
tissue organization, coagulation, inflammation, arthritis,
angiogenesis and cell migration. The product of this gene plays a
major role in growth and in skin, lens, and heart development. It
is also a candidate gene for autosomal recessive Weill-Marchesani
syndrome.
Background References:
- Morales, J., et al. Am. J. Hum. Genet. 85(5):558-568(2009)
- Ben Yahia, S., et al. J. Hum. Genet. 54(9):550-553(2009)
- Kutz, W.E., et al. Hum. Mutat. 29(12):1425-1434(2008)
- Gudbjartsson, D.F., et al. Nat. Genet. 40(5):609-615(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ADAMTS10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 210-240 amino acids from the N-terminal region of human ADAMTS10.
NCBI Gene ID #:
81794
NCBI Official Name:
A disintegrin and metalloproteinase with thrombospondin motifs 10
NCBI Official Symbol:
ADAMTS10
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
121 kDa
Protein Accession #:
Q9H324
Protein GI Number:
148887344
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q9H324
User NOte:
Optimal dilutions for each application to be determined by the researcher.