ASCL2 Antibody

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ProSci
Product Code: PSI-55-538
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-55-538-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse bladder tissue lysates (35ug/lane).
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Western blot analysis in mouse bladder tissue lysates (35ug/lane).

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Further Information

Additional Names:
Achaete-scute homolog 2, ASH-2, hASH2, Class A basic helix-loop-helix protein 45, bHLHa45, Mash2, ASCL2, BHLHA45, HASH2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.
Background References:
  • Stange, D.E., et al. Gut 59(9):1236-1244(2010)
  • Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009)
  • Barrett, J.C., et al. Nat. Genet. 41(6):703-707(2009)
  • Shahib, M.N., et al.Reprod Med 51(11):892-896(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat, Xenopus, Bovine, Zebrafish
Immunogen:
This ASCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-65 amino acids from the N-terminal region of human ASCL2.
NCBI Gene ID #:
430
NCBI Official Name:
Achaete-scute homolog 2
NCBI Official Symbol:
ASCL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
20 kDa
Protein Accession #:
Q99929
Protein GI Number:
12644476
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q99929
User NOte:
Optimal dilutions for each application to be determined by the researcher.