DDX4 Antibody
| Code | Size | Price |
|---|
| PSI-59-092-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Probable ATP-dependent RNA helicase DDX4, DEAD box protein 4, Vasa homolog, DDX4, VASA
Application Note:
For WB starting dilution is: 1:1000
Background:
DEAD box proteins, characterized by the conserved motif
Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are
implicated in a number of cellular processes involving alteration
of RNA secondary structure such as translation initiation, nuclear
and mitochondrial splicing, and ribosome and spliceosome assembly.
Based on their distribution patterns, some members of this family
are believed to be involved in embryogenesis, spermatogenesis, and
cellular growth and division. This gene encodes a DEAD box protein,
which is a homolog of VASA proteins in Drosophila and several other
species. The gene is specifically expressed in the germ cell
lineage in both sexes and functions in germ cell development.
Multiple transcript variants encoding different isoforms have been
found for this gene.
Background References:
- Tilgner, K., et al. Stem Cells 28(1):84-92(2010)
- Sugimoto, K., et al. J. Hum. Genet. 54(8):450-456(2009)
- Hashimoto, H., et al. Gynecol. Oncol. 111(2):312-319(2008)
- Albamonte, M.S., et al. Hum. Reprod. 23(8):1895-1901(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This DDX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-131 amino acids from the N-terminal region of human DDX4.
NCBI Gene ID #:
54514
NCBI Official Name:
Probable ATP-dependent RNA helicase DDX4
NCBI Official Symbol:
DDX4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
79 kDa
Protein Accession #:
Q9NQI0
Protein GI Number:
20138033
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
Q9NQI0
User NOte:
Optimal dilutions for each application to be determined by the researcher.