PAX7 Antibody
Code | Size | Price |
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PSI-55-213-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Paired box protein Pax-7, HuP1, PAX7, HUP1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
PAX7 is a member of the paired box (PAX) family of
transcription factors. Members of this gene family typically
contain a paired box domain, an octapeptide, and a paired-type
homeodomain. These genes play critical roles during fetal
development and cancer growth. The specific function of the paired
box 7 gene is unknown but speculated to involve tumor suppression
since fusion of this gene with a forkhead domain family member has
been associated with alveolar rhabdomyosarcoma. Three transcript
variants encoding different isoforms have been found for this gene.
Background References:
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Williamson, D., et al. J. Clin. Oncol. 28(13):2151-2158(2010)
- Xynos, A., et al. Stem Cells 28(5):965-973(2010)
- Edwards, T.L., et al. Ann. Hum. Genet. 74(2):97-109(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PAX7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-437 amino acids from the C-terminal region of human PAX7.
NCBI Gene ID #:
5081
NCBI Official Name:
Paired box protein Pax-7
NCBI Official Symbol:
PAX7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
57 kDa
Protein Accession #:
P23759
Protein GI Number:
8247951
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,Signal Transduction
Swissprot #:
P23759
User NOte:
Optimal dilutions for each application to be determined by the researcher.