ATF2 Antibody
| Code | Size | Price |
|---|
| PSI-58-769-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cyclic AMP-dependent transcription factor ATF-2, cAMP-dependent transcription factor ATF-2, Activating transcription factor 2, Cyclic AMP-responsive element-binding protein 2, CREB-2, cAMP-responsive element-binding protein 2, HB16, Histone acetyltransferase ATF2, cAMP response element-binding protein CRE-BP1, ATF2, CREB2, CREBP1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a transcription factor that is a member
of the leucine zipper family of DNA binding proteins. This protein
binds to the cAMP-responsive element (CRE), an octameric
palindrome. The protein forms a homodimer or heterodimer with c-Jun
and stimulates CRE-dependent transcription. The protein is also a
histone acetyltransferase (HAT) that specifically acetylates
histones H2B and H4 in vitro; thus it may represent a class of
sequence-specific factors that activate transcription by direct
effects on chromatin components. Additional transcript variants
have been identified but their biological validity has not been
determined.
Background References:
- Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
- Carrillo, R.J., et al. Biophys. Chem. 151(3):149-154(2010)
- Lee, S.H., et al. Oncogene 29(37):5182-5192(2010)
- Salameh, A., et al. J. Biol. Chem. 285(30):23096-23104(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ATF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-347 amino acids from the Central region of human ATF2.
NCBI Gene ID #:
1386
NCBI Official Name:
Cyclic AMP-dependent transcription factor ATF-2
NCBI Official Symbol:
ATF2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
P15336
Protein GI Number:
215274241
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
P15336
User NOte:
Optimal dilutions for each application to be determined by the researcher.