GP9 Antibody

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ProSci
Product Code: PSI-59-442
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-442-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse bladder tissue lysates (35ug/lane).
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Western blot analysis in mouse bladder tissue lysates (35ug/lane).

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Further Information

Additional Names:
Platelet glycoprotein IX, GP-IX, GPIX, Glycoprotein 9, CD42a, GP9
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq].
Background References:
  • Munday, A.D., et al. J. Thromb. Haemost. 8(1):163-172(2010)
  • Mo, X., et al. J. Thromb. Haemost. 7(9):1533-1540(2009)
  • Mangin, P.H., et al. J. Thromb. Haemost. 7(9):1550-1555(2009)
  • Strassel, C., et al. Haematologica 94(6):800-810(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GP9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the C-terminal region of human GP9.
NCBI Gene ID #:
2815
NCBI Official Name:
Platelet glycoprotein IX
NCBI Official Symbol:
GP9
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
19 kDa
Protein Accession #:
P14770
Protein GI Number:
2822110
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
P14770
User NOte:
Optimal dilutions for each application to be determined by the researcher.