CD109 Antibody

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ProSci
Product Code: PSI-55-303
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-55-303-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).
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Western blot analysis in mouse cerebellum tissue lysates (35ug/lane).

Documents

Further Information

Additional Names:
CD109 antigen, 150 kDa TGF-beta-1-binding protein, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7, Platelet-specific Gov antigen, p180, r150, CD109, CD109, CPAMD7
Application Note:
For WB starting dilution is: 1:1000
Background:
CD109 is a member of the alpha2-macroglobulin/complement superfamily. The encoded GPI-linked glycoprotein is found on the cell surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signaling of transforming growth factor beta (TGF-beta).
Background References:
  • Nie, Y.M., et al. Transfus Med 20(6):376-382(2010)
  • Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
  • Hagiwara, S., et al. Oncogene 29(15):2181-2191(2010)
  • Bhatti, F.A., et al. Transfus Med 20(2):78-87(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CD109 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 82-109 amino acids from the N-terminal region of human CD109.
NCBI Gene ID #:
135228
NCBI Official Name:
CD109 antigen
NCBI Official Symbol:
CD109
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
162 kDa
Protein Accession #:
Q6YHK3
Protein GI Number:
117949389
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology
Swissprot #:
Q6YHK3
User NOte:
Optimal dilutions for each application to be determined by the researcher.