TREML1 Antibody

Contact us
ProSci
Product Code: PSI-60-060
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-060-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 2
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
2 / 2
Western blot analysis in mouse spleen tissue lysates (35ug/lane).
❮❯

Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Western blot analysis in mouse spleen tissue lysates (35ug/lane).

Documents

Further Information

Additional Names:
Trem-like transcript 1 protein, TLT-1, Triggering receptor expressed on myeloid cells-like protein 1, TREML1, TLT1
Application Note:
For WB starting dilution is: 1:1000
Background:
TREML1 is located in a gene cluster on chromosome 6 with the single Ig variable (IgV) domain activating receptors TREM1 (MIM 605085) and TREM2 (MIM 605086), but it has distinct structural and functional properties. TREML1 enhances calcium signaling in an SHP2 (PTPN11; MIM 176876)-dependent manner (Allcock et al., 2003 [PubMed 12645956]; Barrow et al., 2004 [PubMed 15128762]).[supplied by OMIM].
Background References:
  • Morales, J., et al. Blood Coagul. Fibrinolysis 21(3):229-236(2010)
  • Washington, A.V., et al. J. Clin. Invest. 119(6):1489-1501(2009)
  • Ford, J.W., et al. Curr. Opin. Immunol. 21(1):38-46(2009)
  • Nurden, A.T., et al. Thromb. Haemost. 100(1):45-51(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TREML1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-241 amino acids from the C-terminal region of human TREML1.
NCBI Gene ID #:
340205
NCBI Official Name:
Trem-like transcript 1 protein
NCBI Official Symbol:
TREML1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
33 kDa
Protein Accession #:
Q86YW5
Protein GI Number:
116256098
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Immunology,Signal Transduction
Swissprot #:
Q86YW5
User NOte:
Optimal dilutions for each application to be determined by the researcher.