NEO1 Antibody
Code | Size | Price |
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PSI-59-445-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Neogenin, Immunoglobulin superfamily DCC subclass member 2, NEO1, IGDCC2, NGN
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a cell surface protein that is a member
of the immunoglobulin superfamily. The encoded protein consists of
four N-terminal immunoglobulin-like domains, six fibronectin type
III domains, a transmembrane domain and a C-terminal internal
domain that shares homology with the tumor suppressor candidate
gene DCC. This protein may be involved in cell growth and
differentiation and in cell-cell adhesion. Defects in this gene are
associated with cell proliferation in certain cancers. Alternate
splicing results in multiple transcript variants. [provided by
RefSeq].
Background References:
- Bradford, D., et al. J. Comp. Neurol. 518(16):3237-3253(2010)
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Zhang, A.S., et al. J. Biol. Chem. 284(34):22580-22589(2009)
- Fujita, Y., et al. Cell Death Differ. 15(10):1593-1608(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This NEO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 657-685 amino acids from the Central region of human NEO1.
NCBI Gene ID #:
4756
NCBI Official Name:
Neogenin
NCBI Official Symbol:
NEO1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
160 kDa
Protein Accession #:
Q92859
Protein GI Number:
116242676
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q92859
User NOte:
Optimal dilutions for each application to be determined by the researcher.