TBR1 Antibody

ProSci
Product Code: PSI-59-440
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-59-440-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse bladder tissue lysates (35ug/lane).

Western blot analysis in mouse bladder tissue lysates (35ug/lane).

Further Information

Additional Names:
T-box brain protein 1, T-brain-1, TBR-1, TES-56, TBR1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase. [provided by RefSeq].
Background References:
  • Hillier, L.W., et al. Nature 434(7034):724-731(2005)
  • Stefanovska, A.M., et al. Cancer Res. 61(22):8351-8352(2001)
  • Hsueh, Y.P., et al. Nature 404(6775):298-302(2000)
  • Bulfone, A., et al. Neuron 15(1):63-78(1995)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TBR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-80 amino acids from the N-terminal region of human TBR1.
NCBI Gene ID #:
10716
NCBI Official Name:
T-box brain protein 1
NCBI Official Symbol:
TBR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
74 kDa
Protein Accession #:
Q16650
Protein GI Number:
2501122
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q16650
User NOte:
Optimal dilutions for each application to be determined by the researcher.