SP8 Antibody

ProSci
Product Code: PSI-55-431
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-55-431-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in mouse heart tissue lysates (35ug/lane).

Western blot analysis in mouse heart tissue lysates (35ug/lane).

Further Information

Additional Names:
Transcription factor Sp8, Specificity protein 8, SP8
Application Note:
For WB starting dilution is: 1:1000
Background:
Transcription factor which plays a key role in limb development. Positively regulates FGF8 expression in the apical ectodermal ridge (AER) and contributes to limb outgrowth in embryos (By similarity).
Background References:
  • Lee, M.T., et al. Mol. Psychiatry (2010) In press :
  • Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
  • Barber, M.J., et al. PLoS ONE(3), E9763 (2010) :
  • Eeles, R.A., et al. Nat. Genet. 41(10):1116-1121(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Chicken, Zebrafish, Xenopus
Immunogen:
This SP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-415 amino acids from the C-terminal region of human SP8.
NCBI Gene ID #:
221833
NCBI Official Name:
Transcription factor Sp8
NCBI Official Symbol:
SP8
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
49 kDa
Protein Accession #:
Q8IXZ3
Protein GI Number:
300669678
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q8IXZ3
User NOte:
Optimal dilutions for each application to be determined by the researcher.