KLF12 Antibody
| Code | Size | Price |
|---|
| PSI-58-515-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Krueppel-like factor 12, Transcriptional repressor AP-2rep, KLF12, AP2REP
Application Note:
For WB starting dilution is: 1:1000
Background:
Activator protein-2 alpha (AP-2 alpha) is a
developmentally-regulated transcription factor and important
regulator of gene expression during vertebrate development and
carcinogenesis. The protein encoded by this gene is a member of the
Kruppel-like zinc finger protein family and can repress expression
of the AP-2 alpha gene by binding to a specific site in the AP-2
alpha gene promoter. Repression by the encoded protein requires
binding with a corepressor, CtBP1. Two transcript variants encoding
different isoforms have been found for this gene. [provided by
RefSeq].
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Eyre, S., et al. Ann. Rheum. Dis. 69(7):1407-1408(2010)
- Wieczorek, S., et al. J. Mol. Med. 88(4):413-421(2010)
- Petersen, G.M., et al. Nat. Genet. 42(3):224-228(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This KLF12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-312 amino acids from the C-terminal region of human KLF12.
NCBI Gene ID #:
11278
NCBI Official Name:
Krueppel-like factor 12
NCBI Official Symbol:
KLF12
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
Q9Y4X4
Protein GI Number:
91771555
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q9Y4X4
User NOte:
Optimal dilutions for each application to be determined by the researcher.