CHRNA5 Antibody
| Code | Size | Price |
|---|
| PSI-57-414-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Neuronal acetylcholine receptor subunit alpha-5, CHRNA5, NACHRA5
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a nicotinic
acetylcholine receptor subunit and a member of a superfamily of
ligand-gated ion channels that mediate fast signal transmission at
synapses. These receptors are thought to be heteropentamers
composed of separate but similar subunits. Defects in this gene
have been linked to susceptibility to lung cancer type 2 (LNCR2).
Background References:
- Wessel, J., et al. Neuropsychopharmacology 35(12):2392-2402(2010)
- Erlich, P.M., et al. Hum. Genet. 128(5):491-499(2010)
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Falvella, F.S., et al. J. Natl. Cancer Inst. 102(17):1366-1370(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine
Immunogen:
This CHRNA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the Central region of human CHRNA5.
NCBI Gene ID #:
1138
NCBI Official Name:
Neuronal acetylcholine receptor subunit alpha-5
NCBI Official Symbol:
CHRNA5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
P30532
Protein GI Number:
2506126
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P30532
User NOte:
Optimal dilutions for each application to be determined by the researcher.