GABRG2 Antibody

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ProSci
Product Code: PSI-55-075
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-55-075-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution + human brain lysate Lysates/proteins at 20 ug per lane.
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Western blot analysis in mouse testis tissue lysates (15ug/lane).This demonstrates the detected GABRG2 protein (arrow).
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Western Blot at 1:1000 dilution + human brain lysate Lysates/proteins at 20 ug per lane.
Western blot analysis in mouse testis tissue lysates (15ug/lane).This demonstrates the detected GABRG2 protein (arrow).

Documents

Further Information

Additional Names:
Gamma-aminobutyric acid receptor subunit gamma-2, GABA(A) receptor subunit gamma-2, GABRG2
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100
Background:
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.
Background References:
  • Green, E.K., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (7), 1347-1349 (2010) :
  • Jansen, L.A., et al. Epilepsia 51(8):1456-1467(2010)
  • Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
  • Shi, X., et al. J. Hum. Genet. 55(6):375-378(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Rat, Bovine
Immunogen:
This GABRG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-224 amino acids from the Central region of human GABRG2.
NCBI Gene ID #:
2566
NCBI Official Name:
Gamma-aminobutyric acid receptor subunit gamma-2
NCBI Official Symbol:
GABRG2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
54 kDa
Protein Accession #:
P18507
Protein GI Number:
116242488
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
P18507
User NOte:
Optimal dilutions for each application to be determined by the researcher.