KCNV1 Antibody

ProSci
Product Code: PSI-62-048
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-62-048-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 3
Western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the detected KCNV1 protein (arrow).
2 / 3
KCNV1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
3 / 3

Western blot analysis in mouse heart tissue lysates (15ug/lane).This demonstrates the detected KCNV1 protein (arrow).
KCNV1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded mouse kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Potassium voltage-gated channel subfamily V member 1, Neuronal potassium channel alpha subunit HNKA, Voltage-gated potassium channel subunit Kv81, KCNV1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50
Background:
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium voltage-gated channel subfamily V. This protein is essentially present in the brain, and its role might be to inhibit the function of a particular class of outward rectifier potassium channel types.
Background References:
  • Gutman, G.A., et al. Pharmacol. Rev. 57(4):473-508(2005)
  • Ebihara, M., et al. Gene 325, 89-96 (2004) :
  • Sano, A., et al. Epilepsia 43 SUPPL 9, 26-31 (2002) :
  • Salinas, M., et al. J. Biol. Chem. 272(13):8774-8780(1997)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Rat
Immunogen:
This KCNV1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-166 amino acids from the N-terminal region of human KCNV1.
NCBI Gene ID #:
27012
NCBI Official Name:
Potassium voltage-gated channel subfamily V member 1
NCBI Official Symbol:
KCNV1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
Q6PIU1
Protein GI Number:
160013825
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience
Swissprot #:
Q6PIU1
User NOte:
Optimal dilutions for each application to be determined by the researcher.