LPHN3 Antibody
| Code | Size | Price |
|---|
| PSI-59-359-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Latrophilin-3, Calcium-independent alpha-latrotoxin receptor 3, CIRL-3, Lectomedin-3, LPHN3, KIAA0768, LEC3
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the latrophilin subfamily of
G-protein coupled receptors (GPCR). Latrophilins may function in
both cell adhesion and signal transduction. In experiments with
non-human species, endogenous proteolytic cleavage within a
cysteine-rich GPS (G-protein-coupled-receptor proteolysis site)
domain resulted in two subunits (a large extracellular N-terminal
cell adhesion subunit and a subunit with substantial similarity to
the secretin/calcitonin family of GPCRs) being non-covalently bound
at the cell membrane.
Background References:
- Arcos-Burgos, M., et al. Mol. Psychiatry 15(11):1053-1066(2010)
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Kasperaviciute, D., et al. Brain 133 (PT 7), 2136-2147 (2010) :
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Immunogen:
This LPHN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-397 amino acids from the N-terminal region of human LPHN3.
NCBI Gene ID #:
23284
NCBI Official Name:
Latrophilin-3
NCBI Official Symbol:
LPHN3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
162 kDa
Protein Accession #:
Q9HAR2
Protein GI Number:
47116772
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Growth Factor
Swissprot #:
Q9HAR2
User NOte:
Optimal dilutions for each application to be determined by the researcher.