PDE6C Antibody

ProSci
Product Code: PSI-64-082
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-64-082-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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PDE6C Antibody IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

PDE6C Antibody IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', cGMP phosphodiesterase 6C, PDE6C, PDEA2
Application Note:
For IHC-P starting dilution is: 1:50~100
Background:
PDE6C is the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa.
Background References:
  • Muradov, H., et al. J. Biol. Chem. 284(47):32662-32669(2009) Chang, B., et al. Proc. Natl. Acad. Sci. U.S.A. 106(46):19581-19586(2009) Thiadens, A.A., et al. Am. J. Hum. Genet. 85(2):240-247(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PDE6C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-300 amino acids from the Central region of human PDE6C.
NCBI Gene ID #:
5146
NCBI Official Name:
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
NCBI Official Symbol:
PDE6C
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
99 kDa
Protein Accession #:
P51160
Protein GI Number:
90111861
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
P51160
User NOte:
Optimal dilutions for each application to be determined by the researcher.