SRGAP1 Antibody
| Code | Size | Price |
|---|
| PSI-59-439-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
SLIT-ROBO Rho GTPase-activating protein 1, srGAP1, Rho GTPase-activating protein 13, SRGAP1, ARHGAP13, KIAA1304
Application Note:
For WB starting dilution is: 1:1000
Background:
GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.
Background References:
- Davila, S., et al. Genes Immun. 11(3):232-238(2010)
- Voss, M., et al. BMC Immunol. 10, 53 (2009) :
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
- Olsen, J.V., et al. Cell 127(3):635-648(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SRGAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 469-497 amino acids from the Central region of human SRGAP1.
NCBI Gene ID #:
57522
NCBI Official Name:
SLIT-ROBO Rho GTPase-activating protein 1
NCBI Official Symbol:
SRGAP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
124 kDa
Protein Accession #:
Q7Z6B7
Protein GI Number:
48428624
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Neuroscience,Signal Transduction
Swissprot #:
Q7Z6B7
User NOte:
Optimal dilutions for each application to be determined by the researcher.